Myxobacterial depsipeptide chondramides interrupt SARS-CoV-2 entry by targeting its broad, cell tropic spike protein

Author:

Fernandez Rey Arturo1,Quimque Mark Tristan123ORCID,Notarte Kin Israel4,Manzano Joe Anthony15,Pilapil Delfin Yñigo15,de Leon Von Novi15,San Jose John Jeric1,Villalobos Omar6,Muralidharan Nisha Harur7,Gromiha M. Michael7,Brogi Simone8,Macabeo Allan Patrick G.1ORCID

Affiliation:

1. Laboratory for Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for the Natural and Applied Sciences, University of Santo Tomas, Manila, Philippines

2. The Graduate School, University of Santo Tomas, Manila, Philippines;

3. Chemistry Department, College of Science and Mathematics, Mindanao State University – Iligan Institute of Technology, Tibanga, Iligan City, Philippines

4. Faculty of Medicine and Surgery, University of Santo Tomas, Manila, Philippines

5. Department of Biological Sciences, College of Science, University of Santo Tomas, Manila, Philippines

6. Department of Pharmacy, Faculty of Pharmacy, University of Santo Tomas, Manila, Philippines

7. Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology (IIT) Madras, Chennai, Tamil Nadu, India

8. Department of Pharmacy, University of Pisa, Pisa, Italy

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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