Structural basis for drug resistance conferred by β-tubulin mutations: a molecular modeling study on native and mutated tubulin complexes with epothilone B-Reference-Cited by-同舟云学术

Structural basis for drug resistance conferred by β-tubulin mutations: a molecular modeling study on native and mutated tubulin complexes with epothilone B

Published:2015-07-17 Issue:12 Volume:33 Page:2530-2540
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Navarrete Karen R.,Alderete Joel B.,Jiménez Verónica A.

Funder

FONDECYT

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883

Reference22 articles.

1. Very fast prediction and rationalization of pKa values for protein-ligand complexes

2. Do β-tubulin mutations have a role in resistance to chemotherapy?

3. The Interaction of Microtubules with Stabilizers Characterized at Biochemical and Structural Levels

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Epothilones A and B: The 16-Membered Natural Macrolides as a Fascinating Template for Antibreast Cancer Drug Discovery;Discovery and Development of Anti-Breast Cancer Agents from Natural Products;2021

2. Bioinformatics Based Understanding of Effect of Mutations in the Human β Tubulin Outside Drug Binding Sites and its Significance in Drug Resistance;The Open Bioinformatics Journal;2018-03-13

3. Recent advances in microtubule-stabilizing agents;European Journal of Medicinal Chemistry;2018-01

4. Natural and Nature-Inspired Macrocycles;Practical Medicinal Chemistry with Macrocycles;2017-11-02

5. Molecular modeling study on the tubulin-binding modes of epothilone derivatives: Insight into the structural basis for epothilones activity;Chemical Biology & Drug Design;2017-07-18