Zinc finger protein binding to DNA: an energy perspective using molecular dynamics simulation and free energy calculations on mutants of both zinc finger domains and their specific DNA bases
Author:
Affiliation:
1. Department of Chemistry, Birzeit University, P. O. Box 14 Birzeit, Palestine
2. Department of Nanoengineering, University of California, San Diego, 9500 Gilman Dr., MC-0448, La Jolla, CA 92093-0448, USA
Funder
Fulbright Commission
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/07391102.2015.1068224
Reference49 articles.
1. Designing Transcription Factor Architectures for Drug Discovery
2. The Protein-Binding Potential of C2H2 Zinc Finger Domains
3. Specificity landscapes of DNA binding molecules elucidate biological function
4. Entropic contributions and the influence of the hydrophobic environment in promiscuous protein-protein association
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