Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe’s disease-Reference-Cited by-同舟云学术

Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe’s disease

Published:2020-03-31 Issue:5 Volume:39 Page:1795-1810
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

D Thirumal Kumar¹,Jain Nikita¹,Kumar S Udhaya¹^ORCID,Jena Prangya Paramita¹,Ramamoorthy Siva¹,Priya Doss C George¹,Zayed Hatem²

Affiliation:

1. School of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India

2. Department of Biomedical Sciences, College of Health and Sciences, QU Health, Qatar University, Doha, Qatar

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2020.1742790

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3. Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach

4. A profound computational study to prioritize the disease-causing mutations in PRPS1 gene

5. Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation

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