Computational investigation of the alkaloids of Pilocarpus microphyllus species as phytopharmaceuticals for the inhibition of sterol 14α-demethylase protease of Trypanosoma cruzi

Author:

de Sá Ézio R. A.1234,Souza Janilson L.5,Costa Rayla K. M.3,Barros Rômulo O.4,de Lima Carlos E. B.6,Lima Francisco das C. A.3,Ramos Ricardo M.4

Affiliation:

1. Federal Institute of Education, Science and Technology of Piauí, IFPI, Picos, Piauí, Brazil

2. Graduate Program in Chemistry, Federal University of Piauí, PPGQ/UFPI, Teresina, Piauí, Brazil

3. Research Laboratory of the Computational Quantum Chemistry and Drug Planning Group, Chemistry Department, State University of Piauí, GQQC&PF/UESPI, Teresina, Piauí, Brazil

4. Research Laboratory in Information Systems, Information Department, Environment, Health and Food Production, Federal Institute of Education, Science and Technology of Piauí, LaPeSI/IFPI, Teresina, Piauí, Brazil

5. Federal Institute of Education, Science and Technology of Maranhão, IFMA, Bacabal, Maranhão, Brazil

6. University Hospital, Federal University of Piauí, Discipline of Cardiology, Department of General Practice - Cardiology and Health Sciences Center, DCG/CCS/UFPI, Teresina, Piauí, Brazil

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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