In silico evaluation of molecular interactions between macrocyclic inhibitors with the HCV NS3 protease. Docking and identification of antiviral pharmacophore site

Author:

Lafridi Hind12ORCID,Almalki Faisal A.3ORCID,Ben Hadda Taibi34ORCID,Berredjem Malika5ORCID,Kawsar Sarkar M. A.6ORCID,Alqahtani Ali M.7,Esharkawy Eman R.89,Lakhrissi Brahim10,Zgou Hsaine2

Affiliation:

1. Material Sciences, Processes, Environment and Modeling, Faculty of Sciences, Ibn Zohr University, Agadir, Morocco

2. Polydisciplinary Faculty, Ibn Zohr University, Ouarzazate, Morocco

3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm AlQura University, Makkah, Saudi Arabia

4. Laboratory of Applied Chemistry and Environment, Faculty of Sciences, Mohammed Premier University, Oujda, Morocco

5. Laboratory of Applied Organic Chemistry LCOA, Synthesis of Biomolecules and Molecular Modelling Group, Badji-Mokhtar - Annaba University, Annaba, Algeria

6. Laboratory of Carbohydrate and Nucleoside Chemistry (LCNC), Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong, Bangladesh

7. Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia

8. Department of Plant Ecology and Range Management, Ecology and Dry Lands Agriculture Division, Desert Research Center, Mathef El-Mataria, Egypt

9. Department of Chemistry, Science Faculty for Girls, Northern Border University ARAR, North Region, Saudi Arabia

10. Laboratory of Organic Chemistry, Catalysis, and Environment, Department of Chemistry, Faculty of Sciences, Ibn Tofaïl University, Kenitra, Morocco

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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