Conserved water-mediated recognition and dynamics of NAD+(carboxamide group) to hIMPDH enzyme: water mimic approach toward the design of isoform-selective inhibitor-Reference-Cited by-同舟云学术

Conserved water-mediated recognition and dynamics of NAD+(carboxamide group) to hIMPDH enzyme: water mimic approach toward the design of isoform-selective inhibitor

Published:2013-07-08 Issue:8 Volume:32 Page:1248-1262
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Bairagya Hridoy R.,Mishra Deepak K.,Mukhopadhyay Bishnu P.,Sekar K.

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883

Reference41 articles.

1. An insight to the dynamics of conserved water-mediated salt bridge interaction and interdomain recognition in hIMPDH isoforms

2. Role of Salt Bridge Dynamics in Inter Domain Recognition of Human IMPDH Isoforms: An Insight to Inhibitor Topology for Isoform-II

3. Conserved water mediated recognition and the dynamics of active site Cys 331 and Tyr 411 in hydrated structure of human IMPDH-II

4. Role of the conserved water molecules in the binding of inhibitor to IMPDH-II (human): A study on the water mimic inhibitor design

5. An Insight to the Dynamics of Conserved Water Molecular Triad in IMPDH II (Human): Recognition of Cofactor and Substrate to Catalytic Arg 322

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