Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential cholinesterase/monoamine oxidase dual inhibitors for Alzheimer’s disease-Reference-Cited by-同舟云学术

Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential cholinesterase/monoamine oxidase dual inhibitors for Alzheimer’s disease

Published:2023-11 Issue: Volume: Page:1-19
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

AL-Sharabi Amal A.¹^ORCID,Evren Asaf Evrim¹²,Sağlık Begüm Nurpelin¹,Yurttaş Leyla¹

Affiliation:

1. Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, Eskişehir, Turkey

2. Vocational School of Health Services, Department of Pharmacy Services, Bilecik Seyh Edebali UniversityTurkey

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2274967

Reference50 articles.

1. Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions

2. 1,3,4-Thiadiazole Based Anticancer Agents

3. Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils 1 1Edited by A. R. Fersht

4. The Cholinergic Hypothesis of Geriatric Memory Dysfunction

5. MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains

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