A comprehension on structure guided alignment dependent 3D-QSAR modelling, and molecular dynamics simulation on 2,4-thiazolidinediones as aldose reductase inhibitors for the management of diabetic complications

Author:

Gautam Priyadarshi1ORCID,Bisht Priya1ORCID,Gautam Anupam234ORCID,Gupta Ghanshyam Das5ORCID,Singh Rajveer6ORCID,Verma Sant Kumar1ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, India

2. Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany

3. International Max Planck Research School “From Molecules to Organisms”, Max Planck Institute for Biology Tübingen, Tübingen, Germany

4. Cluster of Excellence: EXC 2124: Controlling Microbes to Fight Infection, University of Tübingen, Tübingen, Germany

5. Department of Pharmaceutics, ISF College of Pharmacy, Moga, India

6. Department of Pharmacognosy, ISF College of Pharmacy, Moga, India

Funder

Science and Engineering Research Board (SERB), Department of Science and Technology (DST), Govt. of India

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Reference36 articles.

1. Current Advances in the Management of Diabetes Mellitus

2. Synthesis and aldose reductase inhibitory activity of some new chromonyl-2,4-thiazolidinediones

3. Synthesis and aldose reductase inhibitory activity of 5-arylidene-2,4-thiazolidinediones

4. Genetics of diabetes mellitus and diabetes complications

5. IDF Diabetes Atlas Tenth Edition (2021). International Diabetes Federation. Retrieved May 1 2023 from https://www.diabetesatlas.org/upload/resources/material/20200302_133351_IDFATLAS10e-final-web.pdf

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