Inter-BRCT linker is probably the most intolerant region of the BRCA1 BRCT domain
Author:
Affiliation:
1. Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
2. Recombinant Proteins Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2274517
Reference65 articles.
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2. Characterization of intrinsically disordered regions in proteins informed by human genetic diversity
3. G1738R is a BRCA1 founder mutation in Greek breast/ovarian cancer patients: evaluation of its pathogenicity and inferences on its genealogical history
4. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
5. Intention to communicate BRCA1/BRCA2 genetic test results to the family.
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