Synthesis, biological evaluation, and computational investigation of ethyl 2,4,6-trisubstituted-1,4-dihydropyrimidine-5-carboxylates as potential larvicidal agents against Anopheles arabiensis

Author:

Duraisamy Ramasamy1ORCID,Al-Shar’i Nizar A.2ORCID,Chandrashekharappa Sandeep3ORCID,Deb Pran Kishore4ORCID,Gleiser Raquel M.5ORCID,Tratrat Christophe6ORCID,Chopra Deepak7ORCID,Muthukurpalya Bhojegowd Madhusudana Reddy8ORCID,Thirumalai Dhakshanamurthy1ORCID,Morsy Mohamed A.69ORCID,Ibrahim Yasmine F.910ORCID,Mohanlall Viresh11ORCID,Venugopala Katharigatta N.611ORCID

Affiliation:

1. Organic Synthesis and Nano-Bio Laboratory, Department of Chemistry, Thiruvalluvar University, Vellore, India

2. Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan

3. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R) Raebareli, Lucknow, UP, India

4. Department of Pharmaceutical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan

5. CREAN-IMBIV (CONICET-UNC), Universidad Nacional de Cordoba, Cordoba, Argentina

6. Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Saudi Arabia

7. Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, Madhya Pradesh, India

8. Department of Chemistry, School of Applied Sciences, REVA University, Bangalore, India

9. Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt

10. Department of Pathological Sciences, Fakeeh College for Medical Sciences, Jeddah, Saudi Arabia

11. Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban, South Africa

Funder

National Research Foundation

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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