Structural and molecular investigation of the impact of S30L and D88N substitutions in G9R protein on coupling with E4R from Monkeypox virus (MPXV)

Author:

Jin Yifan1,Asad Gillani Syed Jawad2,Batool Farah3,Alshabrmi Fahad M.4,Alatawi Eid A.5,Waheed Yasir67ORCID,Mohammad Anwar7,Khan Abbas1,Wei Dong-Qing189

Affiliation:

1. College of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, P.R. China

2. Medicine, University Medical and Dental College, Faisalabad, Pakistan

3. Institute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore, Pakistan

4. Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia

5. Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia

6. Office of Research, Innovation, and Commercialization (ORIC), Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan

7. Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon

8. Zhongjing Research and Industrialization Institute of Chinese Medicine, Zhongguancun Scientific Park, Nanyang, China

9. Peng Cheng Laboratory, Shenzhen, China

Funder

National Key R&D Program of China

Shanghai Pujiang Program

National Science Foundation of China

Science and Technology Commission of Shanghai

Medical and Engineering and Scientific Research at Shanghai Jiao Tong University

China Postdoctoral Science Foundation

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Reference46 articles.

1. The Amber biomolecular simulation programs

2. Monkeypox virus.

3. The vaccinia virus DNA polymerase and its processivity factor

4. HADDOCK:  A Protein−Protein Docking Approach Based on Biochemical or Biophysical Information

5. A critical review on changing epidemiology of human monkeypox-a current threat with multi-country outbreak;Dubey A.;Journal of Pharmaceutical Negative Results,,2022

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