QSAR-driven screening uncovers and designs novel pyrimidine-4,6-diamine derivatives as potent JAK3 inhibitors-Reference-Cited by-同舟云学术

QSAR-driven screening uncovers and designs novel pyrimidine-4,6-diamine derivatives as potent JAK3 inhibitors

Published:2023-12-07 Issue: Volume: Page:1-30
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Faris Abdelmoujoud¹^ORCID,Ibrahim Ibrahim M.²^ORCID,Alnajjar Radwan³^ORCID,Hadni Hanine¹^ORCID,Bhat Mashooq Ahmad⁴^ORCID,Yaseen Muhammad⁵^ORCID,Chakraborty Souvik⁶^ORCID,Alsakhen Nada⁷^ORCID,Shamkh Israa M.⁸^ORCID,Mabood Fazal⁵^ORCID,M. Naglah Ahmed⁹^ORCID,Ullah Ihsan⁵,Ziedan Noha¹⁰^ORCID,Elhallaoui Menana¹

Affiliation:

1. LIMAS, Department of Chemical Sciences, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco

2. Biophysics Department, Faculty of Science, Cairo University, Cairo, Egypt

3. Department of Chemistry, Faculty of Science, University of Benghazi, Benghazi, Libya

4. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

5. Institute of Chemical Sciences, University of Swat, Main Campus, Charbagh, Swat, Pakistan

6. Department of Physiology, Bhairab Ganguly College, Belghoria, Kolkata, West Bengal, India

7. Department of Chemistry, Faculty of Science, The Hashemite University, Zarqa, Jordan

8. Botany and Microbiology Department, Faculty of Science, Cairo University, Cairo, Egypt

9. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

10. Department of Physical, Mathematical and Engineering Science, Faculty of Science, Business and Enterprise, University of Chester, Chester, UK

Funder

King Saud University, Riyadh, Saudi Arabia

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2283168

Reference97 articles.

1. Accelerating drug discovery through tight integration of expert molecular design and predictive scoring

2. Pathogenic and Therapeutic Relevance of JAK/STAT Signaling in Systemic Lupus Erythematosus: Integration of Distinct Inflammatory Pathways and the Prospect of Their Inhibition with an Oral Agent

3. Ion-water interaction potentials derived from free energy perturbation simulations

4. Atkins, P., Atkins, P. W., & de Paula, J. (2014). Atkins’ physical chemistry. Oxford University Press.

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