Molecular interactions of cucurbitacins A and B with anaplastic lymphoma kinase for lung cancer treatment

Author:

Saeed Mohd12ORCID,Alshammari Nawaf12,Saeed Amir23ORCID,Ayyed AL-Shammary Asma4,Alabdallah Nadiyah M.5ORCID,Ahmad Irfan6,Aqil Farrukh7ORCID

Affiliation:

1. Department of Biology, College of Science, University of Hail, Ha’il, Saudi Arabia

2. Medical and Diagnostic Research Centre, University of Hail, Ha’il, Saudi Arabia

3. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia

4. Department of Public Health, College of Public Health and Health Informatics, University of Ha’il, Ha’il, Saudi Arabia

5. Department of Biology, College of Science and Basic & Applied Scientific Research Centre, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

6. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia

7. Department of Medicine and Brown Cancer Center, University of Louisville, Louisville, KY, USA

Funder

University of Hail

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Reference25 articles.

1. Bowers, K. J., Chow, E., Xu, H., Dror, R. O., Eastwood, M. P., Gregersen, B. A., Klepeis, J. L., Kolossvary, I., Moraes, M. A., Sacerdoti, F. D., & Shaw, D. E. (2006). Scalable algorithms for molecular dynamics simulations on commodity clusters. In Proceedings of the 2006 ACM/IEEE Conference on Supercomputing, 84–es. New York: Association for Computing Machinery. https://doi.org/10.1145/1188455.1188544

2. Identifying Lung Cancer Risk Factors in the Elderly Using Deep Neural Networks: Quantitative Analysis of Web-Based Survey Data

3. Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

4. Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway

5. Lung Cancer: Epidemiology, Etiology, and Prevention

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