Molecular mechanisms of Chengshi Beixie Fenqing Decoction based on network pharmacology: pivotal roles of relaxin signaling pathway and its associated target proteins against Benign prostatic hyperplasia
Author:
Affiliation:
1. School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China
2. State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing, China
Funder
National Natural Science Foundation of China
Natural Science Foundation of Jiangsu province
The Natural Science Foundation of the Jiangsu Higher Education Institutions of China
Open Project of the State Key Laboratory of Natural Medicines
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2203237
Reference85 articles.
1. 2-Methoxyestradiol Attenuates Testosterone-Induced Benign Prostate Hyperplasia in Rats through Inhibition of HIF-1α/TGF-β/Smad2 Axis
2. Possible role of the receptor of advanced glycation end products (RAGE) in the clinical course of prostate neoplasia in patients with and without type 2 diabetes mellitus
3. Association of elevated interleukin-17 and angiopoietin-2 with prostate size in benign prostatic hyperplasia
4. The role of prostate inflammation and fibrosis in lower urinary tract symptoms
5. Cyclic GMP/Protein Kinase G Phosphorylation of Smad3 Blocks Transforming Growth Factor-β–Induced Nuclear Smad Translocation
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