Discovery of a new Bcl-2 inhibitor through synthesis, anticancer activity, docking and MD simulations-Reference-Cited by-同舟云学术

Discovery of a new Bcl-2 inhibitor through synthesis, anticancer activity, docking and MD simulations

Published:2023-05-31 Issue: Volume: Page:1-10
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Byadi Said¹^ORCID,Abdoullah Bimoussa²,Fawzi Mourad²,Irrou Ezaddine³,Ait Elmachkouri Younesse³,Oubella Ali²³,Auhmani Aziz²,Morjani Hamid⁴,Labd Taha Mohamed³,Robert Anthony⁵,Aboulmouhajir Aziz¹^ORCID,Ait Itto Moulay Youssef²^ORCID

Affiliation:

1. Team of Photochemistry, Synthesis, Hemisynthesis, Spectroscopy and Chemoinformatics, Laboratory of Organic Synthesis, Extraction and Valorization, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco

2. Département de Chimie, Faculté des Sciences, Laboratoire de Synthèse Organique et Physico-Chimie Moléculaire, Marrakech, Morocco

3. Laboratory of Organic and Physical Chemistry, Applied Bioorganic Chemistry Team, Faculty of Sciences, IBNOU ZOHR University, Agadir, Morocco

4. BioSpectroscopie Translationnelle, BioSpecT - EA7506, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims Cedex, France

5. Equipe MSO, CNRS UMR 7312 Institut de Chimie Moléculaire Université de Reims Champagne-Ardenne, REIMS Cédex 2, France

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2218934

Reference38 articles.

1. Synthesis and biological evaluations of novel isoxazoles and furoxan derivative as anti-inflammatory agents

2. Molecular Dynamics: Survey of Methods for Simulating the Activity of Proteins

3. The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds

4. Heterocyclic analogs of 5,12-naphthacenequinone 16*. Synthesis and properties of new DNA ligands based on 4,11-diaminoanthra[2,3-b]thiophene-5,10-dione

5. Hybrid of the 1,2,3‐triazole nucleus and sesquiterpene skeleton as a potential antitumor agent: Hemisynthesis, molecular structure, Hirshfeld surface analysis, density functional theory, and in vitro cytotoxic and apoptotic effects