The substitutions G245C and G245D in the Zn2+-binding pocket of the p53 protein result in differences of conformational flexibility of the DNA-binding domain-Reference-Cited by-同舟云学术

The substitutions G245C and G245D in the Zn2+-binding pocket of the p53 protein result in differences of conformational flexibility of the DNA-binding domain

Published:2013-01 Issue:1 Volume:31 Page:78-86
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Pintus S.S.,Ivanisenko N.V.,Demenkov P.S.,Ivanisenko T.V.,Ramachandran S.,Kolchanov N.A.,Ivanisenko V.A.

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883

Reference33 articles.

1. A comparison between p53 accumulation determined by immunohistochemistry andTP53mutations as prognostic variables in tumours from breast cancer patients

2. A functional analysis of p53 during early development of xenopus laevis

3. Molecular dynamics with coupling to an external bath

4. Structure, Function, and Aggregation of the Zinc-Free Form of the p53 DNA Binding Domain

5. Binding free energy calculations of adenosine deaminase inhibitors

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