The signaling pathway of dopamine D2 receptor (D2R) activation using normal mode analysis (NMA) and the construction of pharmacophore models for D2R ligands-Reference-Cited by-同舟云学术

The signaling pathway of dopamine D2 receptor (D2R) activation using normal mode analysis (NMA) and the construction of pharmacophore models for D2R ligands

Published:2016-07-27 Issue:9 Volume:35 Page:2040-2048
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Salmas Ramin Ekhteiari¹,Stein Matthias²,Yurtsever Mine³,Seeman Philip⁴,Erol Ismail¹⁵,Mestanoglu Mert¹,Durdagi Serdar¹

Affiliation:

1. Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul, Turkey

2. Molecular Simulations and Design Group, Max Planck Institute for Dynamics of Complex Technical System, Sandtorstrasse 1, 39106 Magdeburg, Germany

3. Department of Chemistry, Istanbul Technical University, Istanbul, Turkey

4. Department of Pharmacology and Psychiatry, University of Toronto, 260 Heath Street West, Unit 605, M5P 3L6 Toronto, Ontario, Canada

5. Department of Chemistry, Gebze Technical University, Gebze, Turkey

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2016.1206487

Reference45 articles.

1. Fingerprinting G-protein-coupled receptors

2. Normal Mode Analysis of Biomolecular Structures: Functional Mechanisms of Membrane Proteins

3. Coarse-grained normal mode analysis in structural biology

4. Harmonic dynamics of proteins: normal modes and fluctuations in bovine pancreatic trypsin inhibitor.

5. Normal mode analysis of protein dynamics

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