Cyclic peptide engineered from phytocystatin inhibitory hairpin loop as an effective modulator of falcipains and potent antimalarial

Author:

Mishra Manasi1,Singh Vigyasa2,Tellis Meenakshi B.3,Joshi Rakesh S.34,Pandey Kailash C.5,Singh Shailja12

Affiliation:

1. Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Uttar Pradesh, India;

2. Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India;

3. Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Pune, India;

4. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India;

5. Parasite-Host Biology Group, ICMR National Institute of Malaria Research, Dwarka, India

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Reference74 articles.

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2. Structural and functional diversity within the cystatin gene family of Hordeum vulgare

3. An improved capping unit for stabilizing the ends of associated β-strands

4. Barrett, A. J., Rawlings, N. D., Davies, M. E. & Machleidt, W. (1986) Cysteine proteinase inhibitors of the cystatin superfamily. In Proteinase Inhibitors (pp. 515–569). Elsevier Amsterdam.

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