Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach-Reference-Cited by-同舟云学术

Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach

Published:2020-09-16 Issue:2 Volume:40 Page:918-930
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Mutlu Ozal¹^ORCID,Ugurel Osman Mutluhan²³^ORCID,Sariyer Emrah⁴^ORCID,Ata Oguz⁵^ORCID,Inci Tugba Gul²^ORCID,Ugurel Erennur²^ORCID,Kocer Sinem⁶^ORCID,Turgut-Balik Dilek²^ORCID

Affiliation:

1. Faculty of Arts and Sciences, Department of Biology, Marmara University, Istanbul, Turkey

2. Faculty of Chemical and Metallurgical Engineering, Department of Bioengineering, Yildiz Technical University, Istanbul, Turkey

3. School of Engineering and Natural Science, Department of Basic Science, Altinbas University, Istanbul, Turkey

4. Vocational School of Health Services, Medical Laboratory Techniques, Artvin Coruh University, Artvin, Turkey

5. School of Engineering and Natural Science, Department of Software Engineering, Altinbas University, Istanbul, Turkey

6. Faculty of Pharmacy, Department of Pharmaceutical Biotechnology, Istanbul Yeni Yuzyil University, Istanbul, Turkey

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2020.1819882

Reference82 articles.

1. Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates

2. GenBank

3. Molecular dynamics with coupling to an external bath

4. Amino Acid Properties and Consequences of Substitutions

5. Predicting protein flexibility through the prediction of local structures

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