Assessment of in vitro inhibitory effects of novel anti MRSA benzoquinolizine fluoroquinolone WCK 771 (levonadifloxacin) and its metabolite on human liver cytochrome P450 enzymes

Author:

Chavan Rajesh1ORCID,Zope Vineet1,Chavan Nilesh1,Shaikh Javeed1,Patil Kiran1ORCID,Yeole Ravindra1ORCID,Bhagwat Sachin1ORCID,Patel Mahesh1ORCID

Affiliation:

1. Wockhardt Research Centre, Aurangabad, India

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Reference31 articles.

1. Bayer HealthCare Pharmaceuticals Inc. (2010). Highlights of prescribing Information: AVELOX (moxifloxacin hydrochloride) Film coated tablet, injection, solution for IV use. Available from: www.accessdata.fda.gov/drugsatfda_docs/label

2. null

3. The Anti-Methicillin-Resistant Staphylococcus aureus Quinolone WCK 771 Has Potent Activity against Sequentially Selected Mutants, Has a Narrow Mutant Selection Window against Quinolone-Resistant Staphylococcus aureus , and Preferentially Targets DNA Gyrase

4.

Levonadifloxacin, a Novel Broad-Spectrum Anti-MRSA Benzoquinolizine Quinolone Agent: Review of Current Evidence

5. Chugh R, Lakdavala F, Bhatia A. (2016). Safety and pharmacokinetics of multiple ascending doses of WCK 771 and WCK 2349. In: Abstracts of the 26th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID); Amsterdam, Netherlands. Abstract P1268. Basel, Switzerland: European Society of Clinical Microbiology and Infectious Diseases.

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