Pharmacokinetics of levonorgestrel and etonogestrel in rat or minipig following intravenous, subcutaneous, or intradermal administration
Author:
Affiliation:
1. Milad Pharmaceutical Consulting LLC, Plymouth, Michigan, United States
2. Innovative Pharma Consulting LLC, Superior Township, Michigan, United States
3. DMG III Pharma Project Management Consulting LLC, East Lyme, Connecticut, United States
Funder
Bill & Melinda Gates Foundation
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2079023
Reference31 articles.
1. Development and validation of sensitive LC/MS/MS method for quantitative bioanalysis of levonorgestrel in rat plasma and application to pharmacokinetics study
2. Pharmacokinetics and Pharmacodynamics of Sterylglucoside-Modified Liposomes for Levonorgestrel Delivery via Nasal Route
3. Plasma levels of levonorgestrel, gestodene, norethisterone and cyproterone acetate on single-dose subcutaneous administration in oily solution in the rat, beagle and rhesus monkey
4. Plasma levels and progestational activity of levonorgestrel after repeated intravenous and subcutaneous administration in the beagle bitch
5. Terminal half-lives in plasma and bioavailability of norethisterone, levonorgestrel, cyproterone acetate and gestodene in rats, beagles and rhesus monkeys
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