<i>In vitro</i> assessment of the inhibitory effect of goreisan extract and its ingredients on the P-glycoprotein drug transporter and cytochrome P-450 metabolic enzymes-Reference-Cited by-同舟云学术

In vitro assessment of the inhibitory effect of goreisan extract and its ingredients on the P-glycoprotein drug transporter and cytochrome P-450 metabolic enzymes

Published:2022-05-04 Issue:5 Volume:52 Page:511-519
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Takiyama Mikina¹,Matsumoto Takashi¹,Kaifuchi Noriko¹,Mizuhara Yasuharu¹,Warabi Eiji²,Ohbuchi Katsuya¹,Mizoguchi Kazushige¹

Affiliation:

1. Tsumura Advanced Technology Research Laboratories, Kampo Research and Development Division, Tsumura and Co, Ibaraki, Japan

2. Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2078750

Reference33 articles.

1. Oryeongsan (Wulingsan), a traditional Chinese herbal medicine, induces natriuresis and diuresis along with an inhibition of the renin–angiotensin–aldosterone system in rats

2. P-Glycoprotein (P-gp) Mediated Efflux in Caco-2 Cell Monolayers: The Influence of Culturing Conditions and Drug Exposure on P-gp Expression Levels

3. Naringin is a Major and Selective Clinical Inhibitor of Organic Anion-Transporting Polypeptide 1A2 (OATP1A2) in Grapefruit Juice

4. Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine

5. Enhanced tamoxifen bioavailability after oral administration of tamoxifen in rats pretreated with naringin

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