Application of quantitative pharmacology analysis to support early clinical development of oncology drugs: dose selection

Author:

Zhang Ningyuan1,Li Yu1,Cui Wenbin1,Yu Xiangqing1,Huang Ying1

Affiliation:

1. Hansoh Pharmaceutical Group, Shanghai, China

Publisher

Informa UK Limited

Reference22 articles.

1. Patient-derived xenograft (PDX) models, applications and challenges in cancer research

2. Carretero-Iglesia Pihlgren M Berret J Drake A Pais D Dreyfus C Menon V Matthes T Edwards C Edwards J et al. 2024. 2024-AACR abst#1238. AACR2024_Regular_Abstracts_04-01-24.pdf.

3. E14509 abstract;J Clin Oncol,2023

4. Cross D. 2016. The journey of osimertinib discovery: from the lab to the clinic. 2016 FDA-AACR Workshop Pages 105–126.

5. First-in-Man Phase I Trial of the Selective MET Inhibitor Tepotinib in Patients with Advanced Solid Tumors

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