Cytotoxicity of safrole in HepaRG cells: studies on the role of CYP1A2-mediated ortho-quinone metabolic activation-Reference-Cited by-同舟云学术

Cytotoxicity of safrole in HepaRG cells: studies on the role of CYP1A2-mediated ortho-quinone metabolic activation

Published:2019-06-19 Issue:12 Volume:49 Page:1504-1515
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Hu Linlin¹,Wu Fei²,He Jie¹,Zhong Lingjun¹,Song Yifan¹,Shao Hua¹

Affiliation:

1. The Pharmaceutical Department, Nanjing Zhong-da Hospital, School of Medicine, Southeast University, Nanjing, P.R. China;

2. Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China

Funder

National Natural Science Foundation of China (NSFC

Natural Science Foundation of Jiangsu Province of China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2019.1590882

Reference38 articles.

1. Ortho-quinone-enhanced ascorbate oxidation. Combined roles of lipid charge and the magnesium cation

2. Multicomponent Condensation Reactions via ortho-Quinone Methides

3. The HepaRG cell line: a uniquein vitrotool for understanding drug metabolism and toxicology in human

4. EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS

5. LC-MS/MS reveals the formation of reactive ortho -quinone and iminium intermediates in saracatinib metabolism: Phase I metabolic profiling

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