The pharmacokinetics of dabigatran in a rat model of hyperlipidemia induced by poloxamer 407
Author:
Affiliation:
1. College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, South Korea
Funder
National Research Foundation of Korea
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2024.2404168
Reference39 articles.
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2. Bang WS Hwang YR Li Z Lee I Kang HE. 2019. Effects of orotic acid-induced non-alcoholic fatty liver on the pharmacokinetics of metoprolol and its metabolites in rats. J Pharm Pharm Sci. 22:98–111.
3. Blech S Ebner T Ludwig-Schwellinger E Stangier J Roth W. 2008. The metabolism and disposition of the oral direct thrombin inhibitor dabigatran in humans. Drug Metab Dispos. 36:386–399.
4. Bouhajib M Tayab Z. 2020. A pharmacokinetic evaluation of dabigatran etexilate total dabigatran and unconjugated dabigatran following the administration of dabigatran etexilate mesylate capsules in healthy male and female subjects. Drug Res (Stuttg). 70:33–40.
5. Brocks DR Chaudhary HR Ben-Eltriki M Elsherbiny ME El-Kadi AO. 2014. Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. Can J Physiol Pharmacol. 92:140–148.
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