Pharmacokinetic changes of clozapine and norclozapine in a rat model of non-alcoholic fatty liver disease induced by orotic acid-Reference-Cited by-同舟云学术

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Pharmacokinetic changes of clozapine and norclozapine in a rat model of non-alcoholic fatty liver disease induced by orotic acid

Published:2020-11-29 Issue:3 Volume:51 Page:324-334
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Li Zhengri¹,Lee Song Hee¹,Jeong Hee Jin¹,Kang Hee Eun¹

Affiliation:

1. College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, South Korea

Funder

National Research Foundation of Korea

the Korean government

Research Fund

of The Catholic University of Korea

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2020.1851070

Reference50 articles.

1. Tissue Concentrations of Clozapine and its Metabolites in the Rat

2. Effects of Orotic Acid-Induced Non-Alcoholic Fatty Liver on the Pharmacokinetics of Metoprolol and its Metabolites in Rats

3. Changes in plasma protein binding have little clinical relevance

4. In vitro P-glycoprotein affinity for atypical and conventional antipsychotics

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pharmacovigilance of Drug-Drug Interactions: A Pharmacokinetic Study on The Combined Oral Administration of Lurasidone and Clozapine in Rats by Using LC-MS/MS;Journal of Pharmaceutical and Biomedical Analysis;2024-09

2. Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells;Toxicology;2023-06

3. The alteration of drug metabolism enzymes and pharmacokinetic parameters in nonalcoholic fatty liver disease: current animal models and clinical practice;Drug Metabolism Reviews;2023-04-28

4. Approbation of a Model of Fat Liver Disease Induced by Orotic Acid;Drug development & registration;2022-11-27

5. A Physiologically Based Pharmacokinetic Model to Predict the Impact of Metabolic Changes Associated with Metabolic Associated Fatty Liver Disease on Drug Exposure;International Journal of Molecular Sciences;2022-10-04

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