The chlorophenoxy herbicide MCPA: a mechanistic basis for the observed differences in toxicological profile in humans and rats versus dogs-Reference-Cited by-同舟云学术

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The chlorophenoxy herbicide MCPA: a mechanistic basis for the observed differences in toxicological profile in humans and rats versus dogs

Published:2022-05-04 Issue:5 Volume:52 Page:498-510
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Gledhill Alex¹^ORCID,Bowen Rachael¹,Bartels Michael²,Bond Andrew³,Chung Git⁴,Brown Colin⁴,Pye Keith⁴,Vora Tarang⁵

Affiliation:

1. ERM Regulatory Services Ltd, Harrogate, United Kingdom of Great Britain and Northern Ireland

2. ToxMetrics.com LLC, Midland, MICH, USA

3. ALBReg Services, Chelmsford, United Kingdom of Great Britain and Northern Ireland

4. Newcells Biotech, Newcastle upon Tyne, United Kingdom of Great Britain and Northern Ireland

5. Simulations Plus, Lancaster, CA, USA

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2100842

Reference27 articles.

1. Review of the pharmacokinetics and metabolism of triclopyr herbicide in mammals: Impact on safety assessments

2. Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics

3. Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition

4. Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling

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