An HPLC-UV validated bioanalytical method for measurement of <i>in vitro</i> phase 1 kinetics of α-synuclein binding bifunctional compounds-Reference-Cited by-同舟云学术

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An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds

Published:2022-08-03 Issue:8 Volume:52 Page:916-927
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Aigbogun Omozojie P.¹,Nwabufo Chukwunonso K.²,Owens Madeline N.³,Allen Kevin J. H.²,Lee Jeremy S.³,Phenix Christopher P.¹,Krol Ed S.²

Affiliation:

1. Department of Chemistry, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

2. Drug Discovery and Development Research Group, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

3. Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2140315

Reference52 articles.

1. The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties

2. Therapeutic approaches to target alpha-synuclein pathology

3. Human cytochrome P450 kinetic studies on six N -2-methoxybenzyl (NBOMe)-derived new psychoactive substances using the substrate depletion approach

4. Design and Development of Molecular Imaging Probes

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Bifunctional Dimer Caffeine-Indan Attenuates α-Synuclein Misfolding, Neurodegeneration and Behavioral Deficits after Chronic Stimulation of Adenosine A1 Receptors;International Journal of Molecular Sciences;2024-08-29

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