Metabolic disposition of WTX101 (bis-choline tetrathiomolybdate) in a rat model of Wilson disease
Author:
Affiliation:
1. Wilson Therapeutics AB, Stockholm, Sweden;
2. Arcinova, Alnwick, Northumberland, UK
Funder
Wilson Therapeutics AB
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1443352
Reference15 articles.
1. Wilson's disease and other neurological copper disorders
2. Treatment of Wilson's disease with tetrathiomolybdate: V. control of free copper by tetrathiomolybdate and a comparison with trientine
3. The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene
4. EASL Clinical Practice Guidelines: Wilson’s disease
5. Excretion of copper complexed with thiomolybdate into the bile and blood in LEC rats
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