Development and validation of probe drug cocktails for the characterization of CYP450-mediated metabolism by human heart microsomes
Author:
Affiliation:
1. CRCHUM, University of Montreal, Montreal, Canada;
2. Faculty of Pharmacy, University of Montreal, Montreal, Canada;
3. College of Pharmacy, University of Florida, Lake Nona Campus, Orlando, FL, USA
Funder
Canadian Institutes of Health Research
Fondation du CHUM
Fonds de Recherche Santé Québec
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1438684
Reference34 articles.
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2. A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors (Short Communication)
3. Why is uncompetitive inhibition so rare?
4. Detection of Human CYP2C8, CYP2C9, and CYP2J2 in Cardiovascular Tissues
5. Structure and Chemistry of Cytochrome P450
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