Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms-Reference-Cited by-同舟云学术

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Published:2018-06-07 Issue:5 Volume:49 Page:528-539
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Nigade Prashant B.¹,Gundu Jayasagar¹,Pai K. Sreedhara²^ORCID,Nemmani Kumar V. S.³,Talwar Rashmi³

Affiliation:

1. Department of Drug Metabolism and Pharmacokinetics, Lupin Limited (Research Park), Pune, India;

2. Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India;

3. Department of Pharmacology, Lupin Limited (Research Park), Pune, India

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1474399

Reference41 articles.

1. The Integration of Pharmacokinetics and Pharmacodynamics: Understanding Dose-Response

2. Arundel PA. (1997). A multi-compartmental model generally applicable to physiologically-based pharmacokinetics. Thirds IFAC Symposium; 1997 Mar 23–26; University of Warwick, UK.

3. Incorporation of lysosomal sequestration in the mechanistic model for prediction of tissue distribution of basic drugs

4. Volume of Distribution at Steady State for a Linear Pharmacokinetic System with Peripheral Elimination

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes;The AAPS Journal;2023-04-13

2. A PBPK Model of Ternary Cyclodextrin Complex of ST-246 Was Built to Achieve a Reasonable IV Infusion Regimen for the Treatment of Human Severe Smallpox;Frontiers in Pharmacology;2022-03-16

3. Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR Methods;Journal of Pharmaceutical Sciences;2021-04

4. Predicting Volume of Distribution in Humans: Performance of In Silico Methods for a Large Set of Structurally Diverse Clinical Compounds;Drug Metabolism and Disposition;2020-11-25

5. Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat;Drug Metabolism and Disposition;2020-11-04