The potential role of human multidrug resistance protein 1 (MDR1) and multidrug resistance-associated protein 2 (MRP2) in the transport of Huperzine A in vitro-Reference-Cited by-同舟云学术

The potential role of human multidrug resistance protein 1 (MDR1) and multidrug resistance-associated protein 2 (MRP2) in the transport of Huperzine A in vitro

Published:2019-06-09 Issue:3 Volume:50 Page:354-362
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Fei Ziyan¹²,Hu Mengyun¹²,Baum Larry³⁴,Kwan Patrick⁵⁶,Hong Tao⁷,Zhang Chunbo¹²^ORCID

Affiliation:

1. School of Pharmacy, Nanchang University, Nanchang, PR China;

2. Provincial Key Laboratory for Drug Targeting and Drug Screening Research, Nanchang, PR China;

3. The State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Pokfulam, Hong Kong, PR China;

4. Centre for Genomic Sciences, University of Hong Kong, Pokfulam, Hong Kong, PR China;

5. Department of Neuroscience, Alfred Hospital, Monash University, Melbourne, Australia;

6. Departments of Medicine and Neurology, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Australia;

7. Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, Nanchang, PR China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Science and Technology Project of Jiangxi Provincial Education Department

Science and Technology Project of Health and Family Planning Commission of Jiangxi Provence

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2019.1623935

Reference48 articles.

1. Localization of Breast Cancer Resistance Protein (BCRP) in Microvessel Endothelium of Human Control and Epileptic Brain

2. Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development

3. Progress report on new antiepileptic drugs: A summary of the Twelfth Eilat Conference (EILAT XII)

4. In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein

5. [+]-Huperzine A treatment protects against N-methyl-d-aspartate-induced seizure/status epilepticus in rats

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