Mechanism-based pharmacokinetic–pharmacodynamic (PK–PD) modeling and simulation of oxaliplatin for hematological toxicity in rats-Reference-Cited by-同舟云学术

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Mechanism-based pharmacokinetic–pharmacodynamic (PK–PD) modeling and simulation of oxaliplatin for hematological toxicity in rats

Published:2019-04-25 Issue:2 Volume:50 Page:146-153
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Kobuchi Shinji¹,Katsuyama Yosuke¹,Ito Yukako¹

Affiliation:

1. Department of Pharmacokinetics, Kyoto Pharmaceutical University, Kyoto, Japan

Funder

Japan Society for the Promotion of Science

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2019.1601790

Reference22 articles.

1. Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer

2. Oxaliplatin-induced immune mediated thrombocytopenia

3. Transit and lifespan in neutrophil production: implications for drug intervention

4. Population pharmacokinetics of peritoneal, plasma ultrafiltrated and protein-bound oxaliplatin concentrations in patients with disseminated peritoneal cancer after intraperitoneal hyperthermic chemoperfusion of oxaliplatin following cytoreductive surgery: correlation between oxaliplatin exposure and thrombocytopenia

5. Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin

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