Site-specific oxidation of flavanone and flavone by cytochrome P450 2A6 in human liver microsomes-Reference-Cited by-同舟云学术

Site-specific oxidation of flavanone and flavone by cytochrome P450 2A6 in human liver microsomes

Published:2018-09-28 Issue:7 Volume:49 Page:791-802
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Nagayoshi Haruna¹,Murayama Norie²,Kakimoto Kensaku¹,Takenaka Shigeo³,Katahira Jun⁴,Lim Young-Ran⁵,Kim Vitchan⁵,Kim Donghak⁵,Yamazaki Hiroshi²^ORCID,Komori Masayuki⁴,Guengerich F. Peter⁶,Shimada Tsutomu⁴

Affiliation:

1. Osaka Institute of Public Health, Osaka, Japan;

2. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan;

3. Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino Osaka, Japan;

4. Laboratory of Cellular and Molecular Biology, Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan;

5. Department of Biological Sciences, Konkuk University, Seoul, Korea;

6. Department of Biochemistry Vanderbilt University School of Medicine, Nashville, Tennessee, USA

Funder

JSPS

National Research Foundation of Korea

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1505064

Reference55 articles.

1. Identification of a cytochrome P450 cDNA encoding (2S )-flavanone 2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II 1

2. Molecular Cloning and Biochemical Characterization of a Novel Cytochrome P450, Flavone Synthase II, that Catalyzes Direct Conversion of Flavanones to Flavones

3. Flavonoids as components of biologically active cosmeceuticals

4. Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes

5. Simultaneous Chiral Separation of Flavanone, Naringenin, and Hesperetin Enantiomers by RP-UHPLC-DAD

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