The potent mechanism-based inactivation of CYP2D6 and CYP3A4 with fusidic acid in in vivo bioaccumulation-Reference-Cited by-同舟云学术

The potent mechanism-based inactivation of CYP2D6 and CYP3A4 with fusidic acid in in vivo bioaccumulation

Published:2017-11-10 Issue:10 Volume:48 Page:999-1005
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Lin Xiu-Xian¹²,Lian Guang-Hui³,Xu Ying¹²,Zhao Qing¹²,Xiao Jian⁴,Peng Shi-Fang⁵⁶,Xiao Mei-Fang⁵⁶,Ouyang Dong-Sheng¹²,Tan Zhi-Rong¹²,Wang Yi-Cheng¹²,Peng Jing-Bo¹²,Zhang Wei¹²,Chen Yao¹²

Affiliation:

1. Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China,

2. Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, China,

3. Department of gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China,

4. Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China,

5. Department of Hepatology and Infectious Diseases, Xiangya Hospital, Central South University, Changsha, Hunan, China, and

6. Health Management Center, Xiangya Hospital, Central South University, Changsha, Hunan, China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2017.1390628

Reference26 articles.

1. Population Pharmacokinetics of Fusidic Acid: Rationale for Front-Loaded Dosing Regimens Due to Autoinhibition of Clearance

2. Presumed interaction of fusidic acid with simvastatin

3. Screening of drug metabolizing enzymes for fusidic acid and its interactions with isoform-selective substrates in vitro

4. FUCIDIN

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