In vitro inhibition of human UGT isoforms by ritonavir and cobicistat-Reference-Cited by-同舟云学术

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In vitro inhibition of human UGT isoforms by ritonavir and cobicistat

Published:2017-09-11 Issue:8 Volume:48 Page:764-769
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Algeelani Sara¹,Alam Novera¹,Hossain Md Amin¹,Mikus Gerd²,Greenblatt David J.¹³

Affiliation:

1. Graduate Program in Pharmacology and Drug Development, Sackler School of Graduate Biomedical Sciences, Boston, MA, USA,

2. Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Heidelberg, Germany, and

3. Department of Integrative Physiology and Pathobiology, Tufts University School of Medicine, Boston, MA, USA

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2017.1370655

Reference35 articles.

1. Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers

2. Apparent Mechanism-based Inhibition of Human CYP2D6 in Vitro by Paroxetine: Comparison with Fluoxetine and Quinidine

3. Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases

4. Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system

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