Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3-Reference-Cited by-同舟云学术

Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3

Published:2017-01-12 Issue:1 Volume:48 Page:73-78
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Sato Toshihiro¹,Ito Hajime²,Hirata Ayaka³,Abe Takaaki⁴⁵⁶,Mano Nariyasu¹³,Yamaguchi Hiroaki¹³

Affiliation:

1. Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, Japan,

2. Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan,

3. Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan,

4. Division of Nephrology, Endocrinology, and Vascular Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan,

5. Division of Medical Science, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan, and

6. Department of Clinical Biology and Hormonal Regulation, Graduate School of Medicine, Tohoku University, Sendai, Japan

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2016.1275880

Reference28 articles.

1. Identification of a Novel Gene Family Encoding Human Liver-specific Organic Anion Transporter LST-1

2. Thyroid hormone transporters: recent advances

3. Phase I Safety, Pharmacokinetic, and Pharmacodynamic Trial of ZD1839, a Selective Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Five Selected Solid Tumor Types

4. The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance

5. Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

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