Utilizing single- and double-transfected cell models expressing human organic anion transporter 1 and human cytochrome P450 1A2 to investigate the interactions with ingredients of herbal medicines-Reference-Cited by-同舟云学术

Utilizing single- and double-transfected cell models expressing human organic anion transporter 1 and human cytochrome P450 1A2 to investigate the interactions with ingredients of herbal medicines

Published:2016-08-02 Issue:7 Volume:47 Page:576-583
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Qin Zhiyuan¹,Zhao Lei¹,Hu Haihong¹,Jiang Huidi¹,Yu Lushan¹,Zeng Su¹

Affiliation:

1. Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2016.1211774

Reference31 articles.

1. Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy

2. Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural

3. Cell cultures as tools in biopharmacy

4. Fluorescence-Based Assay for the Interaction of Small Molecules with the Human Renal Organic Anion Transporter 1

5. Human cell lines, derived from AHH-1 TK+/− human lymphoblasts, genetically engineered for expression of cytochromes P450

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