Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies

Author:

Spilker Mary E.1,Chung Heekyung2,Visswanathan Ravi1,Bagrodia Shubha1,Gernhardt Steven3,Fantin Valeria R.4,Ellies Lesley G.5

Affiliation:

1. Pfizer Worldwide Research and Development, La Jolla Laboratories, San Diego, CA, USA,

2. Department of Medicine, University of California San Diego, La Jolla, CA, USA,

3. Pfizer Worldwide Research and Development, Groton, CT, USA,

4. ORIC Pharmaceuticals, South San Francisco, CA, USA, and

5. Department of Pathology, University of California San Diego, La Jolla, CA, USA

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

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