Investigation of pharmacokinetic properties of a PEGylated bilirubin nanoparticle in male Sprague-Dawley rats using liquid chromatography-quadrupole time-of-flight mass spectrometry-Reference-Cited by-同舟云学术

Investigation of pharmacokinetic properties of a PEGylated bilirubin nanoparticle in male Sprague-Dawley rats using liquid chromatography-quadrupole time-of-flight mass spectrometry

Published:2023-11-16 Issue: Volume: Page:1-36
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Park Seo-jin¹,Lim Jeong-hyeon¹,Lee Jiyu¹,Lee Jeongmin¹,Hwang Sangsoo¹,Kim Hyunjin²,Jo Seunghyun²,Shin Duckhyang²,MA Sang Ho²,Kim Myung L.²,Shin Young G.¹

Affiliation:

1. Institute of Drug Research and Development, College of Pharmacy, Chungnam National University, Daejeon 34134, South Korea

2. Bilix Co., Ltd. C-Suite 604, 338, Gwanggyojungang-ro, Suji-gu, Bldg. Yongin, Gyeonggi, 16942, South Korea

Funder

Korea Drug Development Fund

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2023.2284859

Reference25 articles.

1. Baranano DE Rao M Ferris CD Snyder SH. 2002. Biliverdin reductase: a major physiologic cytoprotectant. Proc Natl Acad Sci U S A. 99(25):16093-16098.

2. Bateman KP Cohen L Emary B Pucci V. 2013. Standardized workflows for increasing efficiency and productivity in discovery stage bioanalysis. Bioanalysis. 5(14):1783-1794.

3. Bulmer AC Coombes JS Blanchfield JT Toth I Fassett RG Taylor SM. 2011. Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration. Br J Pharmacol. 164(7):1857-1870.

4. Bulmer AC Verkade HJ Wagner KH. 2013. Bilirubin and beyond: a review of lipid status in Gilbert's syndrome and its relevance to cardiovascular disease protection. Prog Lipid Res. 52(2):193-205.

5. Cui Y Wu C Li L Shi H Li C Yin S. 2023. Toward nanotechnology-enabled application of bilirubin in the treatment and diagnosis of various civilization diseases. Mater Today Bio. 20:100658.