Molecular dynamics and quantum chemistry-based approaches to identify isoform selective HDAC2 inhibitor – a novel target to prevent Alzheimer’s disease
Author:
Affiliation:
1. Structural Biology and Bio-computing Lab, Department of Bioinformatics, Alagappa University, Karaikudi, India
Funder
DBT
DST
UGC Research Award
ICMR
Publisher
Informa UK Limited
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10799893.2018.1476541
Reference38 articles.
1. A Hundred Years of Alzheimer's Disease Research
2. Targeting HDACs: A Promising Therapy for Alzheimer's Disease
3. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
4. Alzheimer's Disease: The Amyloid Cascade Hypothesis
5. Manipulating the brain with epigenetics
Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Density functional theory (DFT) studies in HDAC-based chemotherapeutics: Current findings, case studies and future perspectives;Computers in Biology and Medicine;2024-06
2. Molecular Dynamics Simulations of HDAC-ligand Complexes Towards the Design of New Anticancer Compounds;Current Topics in Medicinal Chemistry;2023-11
3. Identification of potent histone deacetylase 2 (HDAC2) inhibitors through combined structure and ligand-based designs and molecular modelling approach;Journal of Biomolecular Structure and Dynamics;2023-06-12
4. Identification of potent HDAC 2 inhibitors using E-pharmacophore modelling, structure-based virtual screening and molecular dynamic simulation;Journal of Molecular Modeling;2022-04-13
5. Non-bonding energy directed designing of HDAC2 inhibitors through molecular dynamics simulation;Journal of Biomolecular Structure and Dynamics;2021-10-18
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3