Cholest-4-en-3-one attenuates TGF-β responsiveness by inducing TGF-β receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells

Author:

Chen Chun-Lin123,Wu Deng-Chyang34,Liu Min-Yun5,Lin Ming-Wei36,Huang Hung-Tu17,Huang Yaw-Bin1358,Chen Li-Chai910,Chen Yu-Yu9,Chen Jih-Jung91011,Yang Pei-Hua1,Kao Yu-Chen1,Chen Pei-Yu1

Affiliation:

1. Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung Taiwan, ROC;

2. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University and Academia Sinica, Kaohsiung, Taiwan, ROC;

3. Center for Stem Cell Research, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC;

4. Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC;

5. Taiwan Ocean Research Institute, National Applied Research Laboratories, Kaohsiung, Taiwan, ROC;

6. Department of Pharmacy, School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC;

7. Division of Pathology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC;

8. Faculty of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC;

9. Department of Pharmacy, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan, ROC;

10. Department of Pharmacy and Graduate Institute of Pharmaceutical Technology, Tajen University, Taiwan, ROC;

11. Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan

Funder

Ministry of Science and Technology, Taiwan

NSYSU-KMU Joint Research Project

Kaohsiung Medical University, Aim for the Top Universities Grant

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology,Biochemistry

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