Cyclosporine-A induced cytotoxicity within HepG2 cells by inhibiting PXR mediated CYP3A4/CYP3A5/MRP2 pathway

Author:

Shang Shenglan1,Li Weiliang1,Zhou Fan1,Zhao Yan1,Yu Mengchen1,Tong Ling1,Xin Huawen1,Yu Airong1

Affiliation:

1. Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei Province, PR China

Funder

The National Natural Science Foundation of China

China Postdoctoral Science Foundation

Initial Research Funding for postdoctoral of General Hospital of Central Theater Command

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Reference37 articles.

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3. Acetaminophen (APAP or N-Acetyl-p-Aminophenol) and acute liver failure;Bunchorntavakul C.;Clinics in Liver Disease,2018

4. Membrane vesicles of toxigenic clostridioides difficile affect the metabolism of liver HepG2 cells;Caballano-Infantes E.;Antioxidants (Basel, Switzerland),2023

5. Serum lactic dehydrogenase in the differential diagnosis of acute hepatocellular injury;Cassidy W. M.;Journal of Clinical Gastroenterology,1994

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