Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis
Author:
Affiliation:
1. Department of Biochemistry, Cell Biology Laboratory, University of Madras, Chennai, India
2. Biochemistry and Biotechnology Laboratory, Central Leather Research Institute, Chennai, India
Funder
UGC-BSRV
Publisher
Informa UK Limited
Subject
Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/01480545.2020.1814803
Reference64 articles.
1. Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats
2. Simple method of estimating severity of pulmonary fibrosis on a numerical scale.
3. Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages
4. The TGFβ superfamily in stem cell biology and early mammalian embryonic development
5. Influence of the microenvironment on cell fate determination and migration
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