Long-term consumption of alcohol exacerbates neural lesions by destroying the functional integrity of the blood

Long-term consumption of alcohol exacerbates neural lesions by destroying the functional integrity of the blood–brain barrier

Published:2019-11-20 Issue:1 Volume:45 Page:231-238
ISSN:0148-0545
Container-title:Drug and Chemical Toxicology
language:en
Short-container-title:Drug and Chemical Toxicology

Author:

Wei Jiangping¹²,Qin Lixia¹²,Fu Ying¹²,Dai Yuan²³,Wen Yueqiang²⁴,Xu Shijun¹²^ORCID

Affiliation:

1. School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China

2. Institute of Material Medica, Integration and Transformation for Brain Disorders, CDUTCM, Chengdu, PR China

3. School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China

4. School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China

Funder

National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01480545.2019.1681444

Reference24 articles.

1. Late dual endothelin receptor blockade with bosentan restores impaired cerebrovascular function in diabetes

2. Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models

3. Transport Pathways for Clearance of Human Alzheimer's Amyloid β-Peptide and Apolipoproteins E and J in the Mouse Central Nervous System

4. Mfsd2a is critical for the formation and function of the blood–brain barrier

5. β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Huangqi Gegen decoction ameliorates alcohol-induced cognitive dysfunction via attenuating oxidative stress and enhancing blood-brain barrier integrity in rats through the Keap1-Nrf2/HO-1 signaling pathway;IRAN J BASIC MED SCI;2024

2. Hepatic LRP-1 plays an important role in amyloidosis in Alzheimer's disease mice: Potential role in chronic heavy alcohol feeding;Neurobiology of Disease;2024-09

3. Hepatic LRP-1 plays an important role in amyloidosis in Alzheimer’s disease mice: Potential role in chronic heavy alcohol feeding;2024-03-19

4. The blood-brain barrier, a key bridge to treat neurodegenerative diseases;Ageing Research Reviews;2023-11

5. The influence of physiological and pathological perturbations on blood-brain barrier function;Frontiers in Neuroscience;2023-10-23