N-acetylcysteine potentiates diclofenac toxicity in Saccharomyces cerevisiae: stronger potentiation in ABC transporter mutant strains-Reference-Cited by-同舟云学术

N-acetylcysteine potentiates diclofenac toxicity in Saccharomyces cerevisiae: stronger potentiation in ABC transporter mutant strains

Published:2017-05-15 Issue:1 Volume:41 Page:89-94
ISSN:0148-0545
Container-title:Drug and Chemical Toxicology
language:en
Short-container-title:Drug and Chemical Toxicology

Author:

Al-Attrache Houssein¹²³^ORCID,Chamieh Hala¹,Hamzé Monzer⁴^ORCID,Morel Isabelle²³⁵,Taha Samir¹^ORCID,Abdel-Razzak Ziad¹^ORCID

Affiliation:

1. Laboratory of Applied Biotechnology: Biomolecules, LBA3B – AZM Center, Tripoli, Lebanon;

2. Faculty of Pharmacy, Inserm U991, Rennes, France;

3. Rennes 1 University, Faculty of Pharmacy, Rennes, France;

4. Laboratory of Medical Microbiology, AZM Center, Tripoli, Lebanon;

5. Laboratory of Emergency and Intensive Care, Pontchaillou Hospital, Rennes, France

Funder

Lebanese University

Association AZM

Lebanese University Research funds

MIP-DILI project

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01480545.2017.1320404

Reference42 articles.

1. Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α

2. Diclofenac-associated hepatotoxicity: Analysis of 180 cases reported to the food and drug administration as adverse reactions

3. Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

4. Fatal hepatitis associated with diclofenac.

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