Ginsenoside Re attenuates 8-OH-DPAT-induced serotonergic behaviors in mice via interactive modulation between <i>PKCδ</i> gene and Nrf2-Reference-Cited by-同舟云学术

Ginsenoside Re attenuates 8-OH-DPAT-induced serotonergic behaviors in mice via interactive modulation between PKCδ gene and Nrf2

Published:2022-06-16 Issue:2 Volume:46 Page:281-296
ISSN:0148-0545
Container-title:Drug and Chemical Toxicology
language:en
Short-container-title:Drug and Chemical Toxicology

Author:

Shin Eun-Joo¹^ORCID,Jeong Ji Hoon²^ORCID,Nguyen Bao-Trong¹,Sharma Naveen¹²,Tran Cuong Ngoc Kim¹,Nah Seung-Yeol³,Lee Yi⁴^ORCID,Byun Jae Kyung⁵,Ko Sung Kwon⁶,Kim Hyoung-Chun¹

Affiliation:

1. Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon, South Korea

2. Department of Global Innovative Drugs, College of Medicine, Graduate School of Chung-Ang University, Chung-Ang University, Seoul, Republic of Korea

3. Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine and Bio/Molecular Informatics Center, Konkuk University, Seoul, Republic of Korea

4. Department of Industrial Plant Science & Technology, Chungbuk National University, Chungju, Republic of Korea

5. Korea Society of Forest Environmental Research, Namyangju, Republic of Korea

6. Department of Oriental Medical Food and Nutrition, Semyung University, Jecheon, Republic of Korea

Funder

R&D Program for Forest Science Technology

Korea Forest Service

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01480545.2021.2022689

Reference49 articles.

1. The Serotonin Syndrome

2. Protein Kinase C as a Drug Target Implications for Drug or Diet Prevention and Treatment of Cancer

3. The role of system Xc − in methamphetamine-induced dopaminergic neurotoxicity in mice

4. Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor

5. PKCδ-dependent p47phox activation mediates methamphetamine-induced dopaminergic neurotoxicity

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