SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells

Author:

Zhao Hanjun1,Lu Lu1,Peng Zheng1,Chen Lin-Lei1,Meng Xinjin1,Zhang Chuyuan1,Ip Jonathan Daniel1,Chan Wan-Mui1,Chu Allen Wing-Ho1,Chan Kwok-Hung1,Jin Dong-Yan2ORCID,Chen Honglin1ORCID,Yuen Kwok-Yung13ORCID,To Kelvin Kai-Wang13ORCID

Affiliation:

1. State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People’s Republic of China

2. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People’s Republic of China

3. Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, People’s Republic of China

Funder

Theme-Based Research Scheme

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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