The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron

Author:

Zhang Li1,Li Qianqian12,Liang Ziteng13,Li Tao1,Liu Shuo1,Cui Qianqian1,Nie Jianhui1,Wu Qian4,Qu Xiaowang4,Huang Weijin1,Wang Youchun1ORCID

Affiliation:

1. Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People’s Republic of China

2. Jiangsu Recbio Technology Co., Ltd., Taizhou, People’s Republic of China

3. Graduate School of Peking Union Medical College, Beijing, People’s Republic of China

4. Translational Medicine Institute, The First People’s Hospital of Chenzhou, University of South China, Chenzhou, People’s Republic of China

Funder

National Key Research and Development Program of China

General Program of the National Natural Science Foundation of China

Beijing Municipal Science and Technology Project

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Reference12 articles.

1. Heavily mutated Omicron variant puts scientists on alert

2. WHO. Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern. 2021. https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern.

3. GISAID. 2021. https://www.gisaid.org/hcov19-variants/.

4. SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape

5. Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

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